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Reducing Th2 inflammation through neutralizing IL-4 antibody rescues myelination in IUGR rat brain

BACKGROUND: Intrauterine growth restriction (IUGR) is a common complication of pregnancy and is associated with significant neurological deficits in infants, including white matter damage. Previous work using an animal model of IUGR has demonstrated that IUGR rats exhibit neurobehavioral deficits an...

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Detalles Bibliográficos
Autores principales: Zanno, Allison E., Romer, Micah A., Fox, Lauren, Golden, Thea, Jaeckle-Santos, Lane, Simmons, Rebecca A., Grinspan, Judith B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913005/
https://www.ncbi.nlm.nih.gov/pubmed/31839002
http://dx.doi.org/10.1186/s11689-019-9297-6