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Reducing Th2 inflammation through neutralizing IL-4 antibody rescues myelination in IUGR rat brain
BACKGROUND: Intrauterine growth restriction (IUGR) is a common complication of pregnancy and is associated with significant neurological deficits in infants, including white matter damage. Previous work using an animal model of IUGR has demonstrated that IUGR rats exhibit neurobehavioral deficits an...
Autores principales: | Zanno, Allison E., Romer, Micah A., Fox, Lauren, Golden, Thea, Jaeckle-Santos, Lane, Simmons, Rebecca A., Grinspan, Judith B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913005/ https://www.ncbi.nlm.nih.gov/pubmed/31839002 http://dx.doi.org/10.1186/s11689-019-9297-6 |
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