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Stimulation of prostate cells by the senescence phenotype of epithelial and stromal cells: Implication for benign prostate hyperplasia

Hyperproliferation of prostate transition‐zone epithelial and stromal cells leads to benign prostate hyperplasia (BPH), a prevalent pathology in elderly men. Senescent cells in BPH tissue induce a senescence‐associated secretory phenotype (SASP) which, by generating inflamed microenvironment and rea...

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Detalles Bibliográficos
Autores principales: Jiang, Shoulei, Song, Chung Seog, Chatterjee, Bandana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914307/
https://www.ncbi.nlm.nih.gov/pubmed/31844843
http://dx.doi.org/10.1096/fba.2018-00084