Transcription factor dimerization activates the p300 acetyltransferase

The transcriptional coactivator p300 is a histone lysine acetyltransferase that is typically recruited to transcriptional enhancers and regulates gene expression by acetylating chromatin. Here we show that p300 activation directly depends on the activation and oligomerisation status of transcription...

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Detalles Bibliográficos
Autores principales: Ortega, Esther, Rengachari, Srinivasan, Ibrahim, Ziad, Hoghoughi, Naghmeh, Gaucher, Jonathan, Holehouse, Alex S., Khochbin, Saadi, Panne, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914384/
https://www.ncbi.nlm.nih.gov/pubmed/30323286
http://dx.doi.org/10.1038/s41586-018-0621-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914384/
https://www.ncbi.nlm.nih.gov/pubmed/30323286
http://dx.doi.org/10.1038/s41586-018-0621-1

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