Cargando…

Ets2 suppresses inflammatory cytokines through MAPK/NF-κB signaling and directly binds to the IL-6 promoter in macrophages

Proper activation of Toll-like receptor (TLR)-mediated signaling and production of proinflammatory cytokines are critical for the initiation of innate immunity, while the specific mechanism maintaining inflammatory homeostasis remains mostly unknown. Here, we show that Ets2 is upregulated following...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ma, Xianwei, Jiang, Zhengyu, Li, Na, Jiang, Wei, Gao, Peng, Yang, Mingjin, Yu, Xiya, Wang, Guifang, Zhang, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914388/ https://www.ncbi.nlm.nih.gov/pubmed/31785145 http://dx.doi.org/10.18632/aging.102480

Ejemplares similares

CXCR4 knockdown prevents inflammatory cytokine expression in macrophages by suppressing activation of MAPK and NF-κB signaling pathways
por: Tian, Xue, et al.
Publicado: (2019)

Adiporedoxin suppresses endothelial activation via inhibiting MAPK and NF-κB signaling
por: He, Hui, et al.
Publicado: (2016)

Epac‐2 ameliorates spontaneous colitis in Il‐10 (−/−) mice by protecting the intestinal barrier and suppressing NF‐κB/MAPK signalling
por: Song, Xue, et al.
Publicado: (2021)

Effect of IL-33 on pyroptosis of macrophages in mice with sepsis via NF-κB/p38 MAPK signaling pathway
por: Ke, Jingnuan, et al.
Publicado: (2021)

β-Sitosterol Suppresses LPS-Induced Cytokine Production in Human Umbilical Vein Endothelial Cells via MAPKs and NF-κB Signaling Pathway
por: Bi, Yiming, et al.
Publicado: (2023)

Neoagaro-oligosaccharide monomers inhibit inflammation in LPS-stimulated macrophages through suppression of MAPK and NF-κB pathways
por: Wang, Wei, et al.
Publicado: (2017)

PEBP1 suppresses HIV transcription and induces latency by inactivating MAPK/NF‐κB signaling
por: Yang, Xinyi, et al.
Publicado: (2020)

4-Acetylantroquinonol B inhibits lipopolysaccharide-induced cytokine release and alleviates sepsis through of MAPK and NFκB suppression
por: Chang, Chien-Hsin, et al.
Publicado: (2018)

Galangin suppresses RANKL‐induced osteoclastogenesis via inhibiting MAPK and NF‐κB signalling pathways
por: Li, Xiucheng, et al.
Publicado: (2021)

Atorvastatin inhibits osteoclast differentiation by suppressing NF-κB and MAPK signaling during IL-1β-induced osteoclastogenesis
por: Lee, Won-Seok, et al.
Publicado: (2018)

Lipopolysaccharide-Binding Protein Downregulates Fractalkine through Activation of p38 MAPK and NF-κB
por: Huang, Xia, et al.
Publicado: (2017)

Methane limit LPS-induced NF-κB/MAPKs signal in macrophages and suppress immune response in mice by enhancing PI3K/AKT/GSK-3β-mediated IL-10 expression
por: Zhang, Xu, et al.
Publicado: (2016)

Magnoflorine Ameliorates Lipopolysaccharide-Induced Acute Lung Injury via Suppressing NF-κB and MAPK Activation
por: Guo, Shuai, et al.
Publicado: (2018)

Calycosin Suppresses RANKL-Mediated Osteoclastogenesis through Inhibition of MAPKs and NF-κB
por: Quan, Gui-Hua, et al.
Publicado: (2015)

Artemisia gmelinii Attenuates Lung Inflammation by Suppressing the NF-κB/MAPK Pathway
por: Kim, Seung Yong, et al.
Publicado: (2022)

Tussilagone Inhibits Osteoclastogenesis and Periprosthetic Osteolysis by Suppressing the NF-κB and P38 MAPK Signaling Pathways
por: Hu, Xuantao, et al.
Publicado: (2020)

Anti-Inflammatory Effect of Mangostenone F in Lipopolysaccharide-Stimulated RAW264.7 Macrophages by Suppressing NF-κB and MAPK Activation
por: Cho, Byoung Ok, et al.
Publicado: (2014)

Inflammation, cytokines, the IL-17/IL-6/STAT3/NF-κB axis, and tumorigenesis
por: Chen, Xiao-Wu, et al.
Publicado: (2015)

Fargesin ameliorates osteoarthritis via macrophage reprogramming by downregulating MAPK and NF-κB pathways
por: Lu, Jiansen, et al.
Publicado: (2021)

Immunostimulatory Activities of Theobromine on Macrophages via the Activation of MAPK and NF-κB Signaling Pathways
por: Lee, Hee-Weon, et al.
Publicado: (2022)

Schisandrin B ameliorated chondrocytes inflammation and osteoarthritis via suppression of NF-κB and MAPK signal pathways
por: Ran, Jisheng, et al.
Publicado: (2018)

Trichomonas vaginalis Induces Production of Proinflammatory Cytokines in Mouse Macrophages Through Activation of MAPK and NF-κB Pathways Partially Mediated by TLR2
por: Li, Ling, et al.
Publicado: (2018)

Correction to Epac‐2 ameliorates spontaneous colitis in Il‐10 (−/−) mice by protecting the intestinal barrier and suppressing NF‐κB/MAPK signalling
Publicado: (2023)

Protective Effect of Fluorofenidone Against Acute Lung Injury Through Suppressing the MAPK/NF-κB Pathway
por: Lv, Xin, et al.
Publicado: (2021)

Quercetin Inhibits the Production of IL-1β-Induced Inflammatory Cytokines and Chemokines in ARPE-19 Cells via the MAPK and NF-κB Signaling Pathways
por: Cheng, Shu-Chen, et al.
Publicado: (2019)

Inhibitory Effects of Palmultang on Inflammatory Mediator Production Related to Suppression of NF-κB and MAPK Pathways and Induction of HO-1 Expression in Macrophages
por: Oh, You-Chang, et al.
Publicado: (2014)

4-Hydroxy-7-Methoxycoumarin Inhibits Inflammation in LPS-activated RAW264.7 Macrophages by Suppressing NF-κB and MAPK Activation
por: Kang, Jin Kyu, et al.
Publicado: (2020)

Anti-Neuroinflammatory Effect of Alantolactone through the Suppression of the NF-κB and MAPK Signaling Pathways
por: Tan, Liwei, et al.
Publicado: (2019)

Schisandra extract ameliorates arthritis pathogenesis by suppressing the NF‐κB and MAPK signalling pathways
por: Han, Seong Jae, et al.
Publicado: (2023)

Andrographolide Inhibits Inflammatory Cytokines Secretion in LPS-Stimulated RAW264.7 Cells through Suppression of NF-κB/MAPK Signaling Pathway
por: Li, Yu, et al.
Publicado: (2017)

Renoprotective effect of erythropoietin via modulation of the STAT6/MAPK/NF-κB pathway in ischemia/reperfusion injury after renal transplantation
por: Zhang, Jinhua, et al.
Publicado: (2018)

Corilagin ameliorates macrophages inflammation in atherosclerosis through TLR4-NFκB/MAPK pathway
por: Meng, Da, et al.
Publicado: (2023)

Luteolin Attenuates IL-1β-Induced THP-1 Adhesion to ARPE-19 Cells via Suppression of NF-κB and MAPK Pathways
por: Huang, Wen-Chung, et al.
Publicado: (2020)

Oncostatin M promotes the ox-LDL-induced activation of NLRP3 inflammasomes via the NF-κB pathway in THP-1 macrophages and promotes the progression of atherosclerosis
por: Liu, Cheng, et al.
Publicado: (2022)

Indoxyl Sulfate Promotes Macrophage IL-1β Production by Activating Aryl Hydrocarbon Receptor/NF-κ/MAPK Cascades, but the NLRP3 inflammasome Was Not Activated
por: Wakamatsu, Takuya, et al.
Publicado: (2018)

PKCδ/MAPKs and NF-κB Pathways are Involved in the Regulation of Ingenane-Type Diterpenoids from Euphorbia neriifolia on Macrophage Function
por: Jiang, Mingyan, et al.
Publicado: (2021)

Mulberry fruit prevents LPS-induced NF-κB/pERK/MAPK signals in macrophages and suppresses acute colitis and colorectal tumorigenesis in mice
por: Qian, Zhengjiang, et al.
Publicado: (2015)

Scandoside Exerts Anti-Inflammatory Effect Via Suppressing NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages
por: He, Jingyu, et al.
Publicado: (2018)

TRAF6 Autoubiquitination-Independent Activation of the NFκB and MAPK Pathways in Response to IL-1 and RANKL
por: Walsh, Matthew C., et al.
Publicado: (2008)

Metal Ion Periplasmic-Binding Protein YfeA of Glaesserella parasuis Induces the Secretion of Pro-Inflammatory Cytokines of Macrophages via MAPK and NF-κB Signaling through TLR2 and TLR4
por: Yang, Zhen, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_64038eu0j17j486h9i7651ntnl