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Distinct effects of epirubicin, cisplatin and cyclophosphamide on ovarian somatic cells of prepuberal ovaries

In vitro culture models were used to characterize the effects of chemotherapeutic drugs and of LH on somatic cells from prepuberal mouse ovaries. All cell types (pre- and granulosa cells, pre-thecal and OSE cells) underwent apoptosis following Epirubicin (0.5μM) exposure for 24hrs (about 60%) and 48...

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Detalles Bibliográficos
Autores principales:	Marcozzi, Serena, Rossi, Valerio, Salvatore, Giulia, Di Rella, Francesca, De Felici, Massimo, Klinger, Francesca Gioia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914390/ https://www.ncbi.nlm.nih.gov/pubmed/31711044 http://dx.doi.org/10.18632/aging.102476

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