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Silencing of long non-coding RNA H19 downregulates CTCF to protect against atherosclerosis by upregulating PKD1 expression in ApoE knockout mice

This study aimed to explore the interactions among long non-coding RNA H19, transcriptional factor CCCTC-binding factor (CTCF) and polycystic kidney disease 1 (PKD1), and to investigate its potentially regulatory effect on vulnerable plaque formation and angiogenesis of atherosclerosis. We establish...

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Detalles Bibliográficos
Autores principales: Yang, Yongyao, Tang, Feng, Wei, Fang, Yang, Long, Kuang, Chunyan, Zhang, Hongming, Deng, Jiusheng, Wu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914395/
https://www.ncbi.nlm.nih.gov/pubmed/31757932
http://dx.doi.org/10.18632/aging.102388