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Development and validation of a metastasis-associated prognostic signature based on single-cell RNA-seq in clear cell renal cell carcinoma

Single-cell RNA sequencing (scRNA-seq) was recently adopted for deciphering intratumoral heterogeneity across cell sub-populations, including clear cell renal cell carcinoma (ccRCC). Here, we characterized the single-cell expression profiling of 121 cell samples and found 44 metastasis-associated ma...

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Detalles Bibliográficos
Autores principales: Zhang, Chuanjie, He, Hongchao, Hu, Xin, Liu, Ao, Huang, Da, Xu, Yang, Chen, Lu, Xu, Danfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914399/
https://www.ncbi.nlm.nih.gov/pubmed/31747386
http://dx.doi.org/10.18632/aging.102434