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Mate pair sequencing outperforms fluorescence in situ hybridization in the genomic characterization of multiple myeloma
Fluorescence in situ hybridization (FISH) is currently the gold-standard assay to detect recurrent genomic abnormalities of prognostic significance in multiple myeloma (MM). Since most translocations in MM involve a position effect with heterogeneous breakpoints, we hypothesize that FISH has the pot...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914798/ https://www.ncbi.nlm.nih.gov/pubmed/31844041 http://dx.doi.org/10.1038/s41408-019-0255-z |