B-ALL With t(5;14)(q31;q32); IGH-IL3 Rearrangement and Eosinophilia: A Comprehensive Analysis of a Peculiar IGH-Rearranged B-ALL

Background: B-cell acute lymphoblastic leukemia associated with t(5;14)(q31;q32); IGH-IL3 is an exceptional cause of eosinophilia. The IGH enhancer on 14q32 is juxtaposed to the IL3 gene on 5q31, leading to interleukin-3 overproduction and release of mature eosinophils in the blood. Clinical, biolog...

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Detalles Bibliográficos
Autores principales: Fournier, Benjamin, Balducci, Estelle, Duployez, Nicolas, Clappier, Emmanuelle, Cuccuini, Wendy, Arfeuille, Chloé, Caye-Eude, Aurélie, Delabesse, Eric, Bottollier-Lemallaz Colomb, Elodie, Nebral, Karin, Chrétien, Marie-Lorraine, Derrieux, Coralie, Cabannes-Hamy, Aurélie, Dumezy, Florent, Etancelin, Pascaline, Fenneteau, Odile, Frayfer, Jamile, Gourmel, Antoine, Loosveld, Marie, Michel, Gérard, Nadal, Nathalie, Penther, Dominique, Tigaud, Isabelle, Fournier, Elise, Reismüller, Bettina, Attarbaschi, Andishe, Lafage-Pochitaloff, Marina, Baruchel, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914849/
https://www.ncbi.nlm.nih.gov/pubmed/31921638
http://dx.doi.org/10.3389/fonc.2019.01374

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