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Ligustrazine Prevents Intervertebral Disc Degeneration via Suppression of Aberrant TGFβ Activation in Nucleus Pulposus Cells

OBJECTIVES: Aberrant transforming growth factor β (TGFβ) activation is detrimental to both nucleus pulposus (NP) cells and cartilage endplates (CEPs), which can lead to intervertebral disc degeneration (IDD). Ligustrazine (LIG) reduces the expression of inflammatory factors and TGFβ1 in hypertrophic...

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Detalles Bibliográficos
Autores principales:	Liu, Shufen, Cheng, Yuhao, Tan, Yuqi, Dong, Jingcheng, Bian, Qin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914881/ https://www.ncbi.nlm.nih.gov/pubmed/31886227 http://dx.doi.org/10.1155/2019/5601734

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