Advances in the Research on Anticardiolipin Antibody

Anticardiolipin antibody (ACA) is a kind of autoantibody and is one of the antiphospholipid antibodies (aPLs). Phospholipids with a negative charge on platelets and endothelial cell membranes are ACA target antigens. ACA is common in systemic lupus erythematosus and other autoimmune diseases and is...

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Detalles Bibliográficos
Autores principales: Wang, Dan, Lv, Wenxin, Zhang, Shichang, Zhang, Jiexin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914984/
https://www.ncbi.nlm.nih.gov/pubmed/31886311
http://dx.doi.org/10.1155/2019/8380214
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author Wang, Dan
Lv, Wenxin
Zhang, Shichang
Zhang, Jiexin
author_facet Wang, Dan
Lv, Wenxin
Zhang, Shichang
Zhang, Jiexin
author_sort Wang, Dan
collection PubMed
description Anticardiolipin antibody (ACA) is a kind of autoantibody and is one of the antiphospholipid antibodies (aPLs). Phospholipids with a negative charge on platelets and endothelial cell membranes are ACA target antigens. ACA is common in systemic lupus erythematosus and other autoimmune diseases and is closely associated with thrombosis, thrombocytopenia, and spontaneous abortion. In 1983, Harris established a method for detecting ACA, and research on the antibody has gained worldwide attention and has developed rapidly. For this review, we browsed articles that cover most of the ACA-related studies in the last 25 years and extracted influential ideas and conclusions in this field.
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spelling pubmed-69149842019-12-29 Advances in the Research on Anticardiolipin Antibody Wang, Dan Lv, Wenxin Zhang, Shichang Zhang, Jiexin J Immunol Res Review Article Anticardiolipin antibody (ACA) is a kind of autoantibody and is one of the antiphospholipid antibodies (aPLs). Phospholipids with a negative charge on platelets and endothelial cell membranes are ACA target antigens. ACA is common in systemic lupus erythematosus and other autoimmune diseases and is closely associated with thrombosis, thrombocytopenia, and spontaneous abortion. In 1983, Harris established a method for detecting ACA, and research on the antibody has gained worldwide attention and has developed rapidly. For this review, we browsed articles that cover most of the ACA-related studies in the last 25 years and extracted influential ideas and conclusions in this field. Hindawi 2019-12-01 /pmc/articles/PMC6914984/ /pubmed/31886311 http://dx.doi.org/10.1155/2019/8380214 Text en Copyright © 2019 Dan Wang et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Wang, Dan
Lv, Wenxin
Zhang, Shichang
Zhang, Jiexin
Advances in the Research on Anticardiolipin Antibody
title Advances in the Research on Anticardiolipin Antibody
title_full Advances in the Research on Anticardiolipin Antibody
title_fullStr Advances in the Research on Anticardiolipin Antibody
title_full_unstemmed Advances in the Research on Anticardiolipin Antibody
title_short Advances in the Research on Anticardiolipin Antibody
title_sort advances in the research on anticardiolipin antibody
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914984/
https://www.ncbi.nlm.nih.gov/pubmed/31886311
http://dx.doi.org/10.1155/2019/8380214
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