Cargando…

Palmitic Acid Methyl Ester Induces G(2)/M Arrest in Human Bone Marrow-Derived Mesenchymal Stem Cells via the p53/p21 Pathway

Bone marrow-derived mesenchymal cells (BM-MSCs) are able to differentiate into adipocytes, which can secrete adipokines to affect BM-MSC proliferation and differentiation. Recent evidences indicated that adipocytes can secrete fatty acid metabolites, such as palmitic acid methyl ester (PAME), which...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Jian-Hong, Ting, Pei-Ching, Lee, Wen-Sen, Chiu, Hung-Wen, Chien, Chun-An, Liu, Chin-Hung, Sun, Li-Yi, Yang, Kun-Ta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915012/ https://www.ncbi.nlm.nih.gov/pubmed/31885624 http://dx.doi.org/10.1155/2019/7606238

Ejemplares similares

Palmitic Acid Methyl Ester Enhances Adipogenic Differentiation in Rat Adipose Tissue-Derived Mesenchymal Stem Cells through a G Protein-Coupled Receptor-Mediated Pathway
por: Lin, Jian-Hong, et al.
Publicado: (2021)

Loss of IKKβ activity increases p53 stability and p21 expression leading to cell cycle arrest and apoptosis
por: Yang, Pei-Ming, et al.
Publicado: (2010)

Nuclear targeting of the betanodavirus B1 protein via two arginine-rich domains induces G1/S cell cycle arrest mediated by upregulation of p53/p21
por: Su, Yu-Chin, et al.
Publicado: (2018)

The PPARγ‐SETD8 axis constitutes an epigenetic, p53‐independent checkpoint on p21‐mediated cellular senescence
por: Shih, Chieh‐Tien, et al.
Publicado: (2017)

Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21(Cip1) and p27(Kip1)
por: Lin, Hui-Ping, et al.
Publicado: (2015)

Mouse bone marrow mesenchymal stem cells with distinct p53 statuses display differential characteristics
por: Wang, Bo, et al.
Publicado: (2020)

p53/p21 Pathway Involved in Mediating Cellular Senescence of Bone Marrow-Derived Mesenchymal Stem Cells from Systemic Lupus Erythematosus Patients
por: Gu, Zhifeng, et al.
Publicado: (2013)

Cholesterol Retards Senescence in Bone Marrow Mesenchymal Stem Cells by Modulating Autophagy and ROS/p53/p21(Cip1/Waf1) Pathway
por: Zhang, Mingyu, et al.
Publicado: (2016)

p53-dependent growth arrest and induction of p21: A critical role for PCAF-mediated histone acetylation
por: Eckner, Richard
Publicado: (2012)

LincRNA-p21 leads to G1 arrest by p53 pathway in esophageal squamous cell carcinoma
por: Zhang, Ying, et al.
Publicado: (2019)

The Proapoptotic Gene Bad Regulates Brain Development via p53-Mediated Stress Signals in Zebrafish
por: Hung, Jo-Chi, et al.
Publicado: (2021)

A USP28–53BP1–p53–p21 signaling axis arrests growth after centrosome loss or prolonged mitosis
por: Lambrus, Bramwell G., et al.
Publicado: (2016)

Gatifloxacin Induces S and G(2)-Phase Cell Cycle Arrest in Pancreatic Cancer Cells via p21/p27/p53
por: Yadav, Vikas, et al.
Publicado: (2012)

Transcriptional activation of p21(Waf1) contributes to suppression of HR by p53 in response to replication arrest induced by camptothecin
por: Romanova, Larisa Y., et al.
Publicado: (2018)

Avian Reovirus Protein p17 Functions as a Nucleoporin Tpr Suppressor Leading to Activation of p53, p21 and PTEN and Inactivation of PI3K/AKT/mTOR and ERK Signaling Pathways
por: Huang, Wei-Ru, et al.
Publicado: (2015)

Correction: Avian Reovirus Protein p17 Functions as a Nucleoporin Tpr Suppressor Leading to Activation of p53, p21 and PTEN and Inactivation of PI3K/AKT/mTOR and ERK Signaling Pathways
por: Huang, Wei-Ru, et al.
Publicado: (2015)

Necdin, a p53-Target Gene, Is an Inhibitor of p53-Mediated Growth Arrest
por: Lafontaine, Julie, et al.
Publicado: (2012)

Postprandial triglyceride-rich lipoproteins-induced premature senescence of adipose-derived mesenchymal stem cells via the SIRT1/p53/Ac-p53/p21 axis through oxidative mechanism
por: Xiang, Qun-yan, et al.
Publicado: (2020)

D133P53, directly transactivated by p53, prevents p53-mediated apoptosis without inhibiting p53-mediated cell cycle arrest
por: Aoubala, M, et al.
Publicado: (2010)

CIL-102-Induced Cell Cycle Arrest and Apoptosis in Colorectal Cancer Cells via Upregulation of p21 and GADD45
por: Huang, Wen-Shih, et al.
Publicado: (2017)

Anti-Proliferative Effect of Statins Is Mediated by DNMT1 Inhibition and p21 Expression in OSCC Cells
por: Dongoran, Rachmad Anres, et al.
Publicado: (2020)

Molecular Dynamics Simulation of Palmitate Ester Self-Assembly with Diclofenac
por: Karjiban, Roghayeh Abedi, et al.
Publicado: (2012)

Expressions of p53 and p21 in primary gastric lymphomas.
por: Go, J. H., et al.
Publicado: (2001)

p53-independent p21 induction by MELK inhibition
por: Matsuda, Tatsuo, et al.
Publicado: (2017)

Age‐associated expression of p21and p53 during human wound healing
por: Chia, Chee W., et al.
Publicado: (2021)

Autophagy protects bone marrow mesenchymal stem cells from palmitate-induced apoptosis through the ROS-JNK/p38 MAPK signaling pathways
por: Liu, Yongyi, et al.
Publicado: (2018)

Deficiency of G1 regulators P53, P21(Cip1 )and/or pRb decreases hepatocyte sensitivity to TGFβ cell cycle arrest
por: Sheahan, Sharon, et al.
Publicado: (2007)

Loss of p53 Sensitizes Cells to Palmitic Acid-Induced Apoptosis by Reactive Oxygen Species Accumulation
por: Yu, Guowu, et al.
Publicado: (2019)

Prognostic Significance of p21 and p53 Expression in Gastric Cancer
por: Seo, Young-Ho, et al.
Publicado: (2003)

Endosome traffic machinery meets the p53–p21 axis
por: Barroso-González, Jonathan, et al.
Publicado: (2014)

p21 can be a barrier to ferroptosis independent of p53
por: Venkatesh, Divya, et al.
Publicado: (2020)

Cell cycle regulation: p53-p21-RB signaling
por: Engeland, Kurt
Publicado: (2022)

The RNA helicase p68 (DDX5) is selectively required for the induction of p53-dependent p21 expression and cell cycle arrest after DNA damage
por: Nicol, Samantha M., et al.
Publicado: (2012)

Survivin Loss in Thymocytes Triggers p53-mediated Growth Arrest and p53-independent Cell Death
por: Okada, Hitoshi, et al.
Publicado: (2004)

MSK1 functions as a transcriptional coactivator of p53 in the regulation of p21 gene expression
por: Ahn, Jihye, et al.
Publicado: (2018)

AMPK Activity Contributes to G2 Arrest and DNA Damage Decrease via p53/p21 Pathways in Oxidatively Damaged Mouse Zygotes
por: He, Pei, et al.
Publicado: (2020)

The Antitumor Effect of Caffeic Acid Phenethyl Ester by Downregulating Mucosa-Associated Lymphoid Tissue 1 via AR/p53/NF-κB Signaling in Prostate Carcinoma Cells
por: Chang, Kang-Shuo, et al.
Publicado: (2022)

p53‐independent Induction of p21 (WAF1/CIP1), Reduction of Cyclin B1 and G2/M Arrest by the Isoflavone Genistein in Human Prostate Carcinoma Cells
por: Choi, Yung Hyun, et al.
Publicado: (2000)

Flavopereirine Suppresses the Growth of Colorectal Cancer Cells through P53 Signaling Dependence
por: Li, Jhy-Ming, et al.
Publicado: (2019)

How p53 wields the scales of fate: Arrest or death?
por: Goh, Amanda M., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_pqeh9cr9n39euholi5vseetj4v