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Calycosin-7-O-β-D-glucoside Attenuates OGD/R-Induced Damage by Preventing Oxidative Stress and Neuronal Apoptosis via the SIRT1/FOXO1/PGC-1α Pathway in HT22 Cells

Neuronal apoptosis induced by oxidative stress is a major pathological process that occurs after cerebral ischemia-reperfusion. Calycosin-7-O-β-D-glucoside (CG) is a representative component of isoflavones in Radix Astragali (RA). Previous studies have shown that CG has potential neuroprotective eff...

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Detalles Bibliográficos
Autores principales: Yan, Xiangli, Yu, Aiming, Zheng, Haozhen, Wang, Shengxin, He, Yingying, Wang, Lisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915014/
https://www.ncbi.nlm.nih.gov/pubmed/31885537
http://dx.doi.org/10.1155/2019/8798069