Pigment Epithelial‐Derived Factor Deficiency Accelerates Atherosclerosis Development via Promoting Endothelial Fatty Acid Uptake in Mice With Hyperlipidemia

BACKGROUND: Endothelial cell injury, induced by dyslipidemia, is the initiation of atherosclerosis, resulting in an imbalance in endothelial fatty acid (FA) transport. Pigment epithelial‐derived factor (PEDF) is an important regulator in lipid metabolism. We hypothesized that PEDF is involved in end...

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Detalles Bibliográficos
Autores principales: Wang, Haiping, Yang, Yanfang, Yang, Ming, Li, Xinghui, Tan, Jing, Wu, Yandi, Zhang, Yuling, Li, Yuanlong, Hu, Bo, Deng, Shijie, Yang, Fengmin, Gao, Saifei, Li, Hui, Yang, Zhenyu, Chen, Hui, Cai, Weibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915260/
https://www.ncbi.nlm.nih.gov/pubmed/31711388
http://dx.doi.org/10.1161/JAHA.119.013028

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