On-Site Ribosome Remodeling by Locally Synthesized Ribosomal Proteins in Axons

Ribosome assembly occurs mainly in the nucleolus, yet recent studies have revealed robust enrichment and translation of mRNAs encoding many ribosomal proteins (RPs) in axons, far away from neuronal cell bodies. Here, we report a physical and functional interaction between locally synthesized RPs and...

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Detalles Bibliográficos
Autores principales: Shigeoka, Toshiaki, Koppers, Max, Wong, Hovy Ho-Wai, Lin, Julie Qiaojin, Cagnetta, Roberta, Dwivedy, Asha, de Freitas Nascimento, Janaina, van Tartwijk, Francesca W., Ströhl, Florian, Cioni, Jean-Michel, Schaeffer, Julia, Carrington, Mark, Kaminski, Clemens F., Jung, Hosung, Harris, William A., Holt, Christine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915326/
https://www.ncbi.nlm.nih.gov/pubmed/31825839
http://dx.doi.org/10.1016/j.celrep.2019.11.025

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