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Biocompatible Polymer Materials with Antimicrobial Properties for Preparation of Stents

Biodegradable polymers are promising materials for use in medical applications such as stents. Their properties are comparable to commercially available resistant metal and polymeric stents, which have several major problems, such as stent migration and stent clogging due to microbial biofilm. Conse...

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Autores principales: Škrlová, Kateřina, Malachová, Kateřina, Muñoz-Bonilla, Alexandra, Měřinská, Dagmar, Rybková, Zuzana, Fernández-García, Marta, Plachá, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915381/
https://www.ncbi.nlm.nih.gov/pubmed/31683612
http://dx.doi.org/10.3390/nano9111548
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author Škrlová, Kateřina
Malachová, Kateřina
Muñoz-Bonilla, Alexandra
Měřinská, Dagmar
Rybková, Zuzana
Fernández-García, Marta
Plachá, Daniela
author_facet Škrlová, Kateřina
Malachová, Kateřina
Muñoz-Bonilla, Alexandra
Měřinská, Dagmar
Rybková, Zuzana
Fernández-García, Marta
Plachá, Daniela
author_sort Škrlová, Kateřina
collection PubMed
description Biodegradable polymers are promising materials for use in medical applications such as stents. Their properties are comparable to commercially available resistant metal and polymeric stents, which have several major problems, such as stent migration and stent clogging due to microbial biofilm. Consequently, conventional stents have to be removed operatively from the patient’s body, which presents a number of complications and can also endanger the patient’s life. Biodegradable stents disintegrate into basic substances that decompose in the human body, and no surgery is required. This review focuses on the specific use of stents in the human body, the problems of microbial biofilm, and possibilities of preventing microbial growth by modifying polymers with antimicrobial agents.
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spelling pubmed-69153812019-12-24 Biocompatible Polymer Materials with Antimicrobial Properties for Preparation of Stents Škrlová, Kateřina Malachová, Kateřina Muñoz-Bonilla, Alexandra Měřinská, Dagmar Rybková, Zuzana Fernández-García, Marta Plachá, Daniela Nanomaterials (Basel) Review Biodegradable polymers are promising materials for use in medical applications such as stents. Their properties are comparable to commercially available resistant metal and polymeric stents, which have several major problems, such as stent migration and stent clogging due to microbial biofilm. Consequently, conventional stents have to be removed operatively from the patient’s body, which presents a number of complications and can also endanger the patient’s life. Biodegradable stents disintegrate into basic substances that decompose in the human body, and no surgery is required. This review focuses on the specific use of stents in the human body, the problems of microbial biofilm, and possibilities of preventing microbial growth by modifying polymers with antimicrobial agents. MDPI 2019-10-31 /pmc/articles/PMC6915381/ /pubmed/31683612 http://dx.doi.org/10.3390/nano9111548 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Škrlová, Kateřina
Malachová, Kateřina
Muñoz-Bonilla, Alexandra
Měřinská, Dagmar
Rybková, Zuzana
Fernández-García, Marta
Plachá, Daniela
Biocompatible Polymer Materials with Antimicrobial Properties for Preparation of Stents
title Biocompatible Polymer Materials with Antimicrobial Properties for Preparation of Stents
title_full Biocompatible Polymer Materials with Antimicrobial Properties for Preparation of Stents
title_fullStr Biocompatible Polymer Materials with Antimicrobial Properties for Preparation of Stents
title_full_unstemmed Biocompatible Polymer Materials with Antimicrobial Properties for Preparation of Stents
title_short Biocompatible Polymer Materials with Antimicrobial Properties for Preparation of Stents
title_sort biocompatible polymer materials with antimicrobial properties for preparation of stents
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915381/
https://www.ncbi.nlm.nih.gov/pubmed/31683612
http://dx.doi.org/10.3390/nano9111548
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