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Biocompatible Polymer Materials with Antimicrobial Properties for Preparation of Stents
Biodegradable polymers are promising materials for use in medical applications such as stents. Their properties are comparable to commercially available resistant metal and polymeric stents, which have several major problems, such as stent migration and stent clogging due to microbial biofilm. Conse...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915381/ https://www.ncbi.nlm.nih.gov/pubmed/31683612 http://dx.doi.org/10.3390/nano9111548 |
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author | Škrlová, Kateřina Malachová, Kateřina Muñoz-Bonilla, Alexandra Měřinská, Dagmar Rybková, Zuzana Fernández-García, Marta Plachá, Daniela |
author_facet | Škrlová, Kateřina Malachová, Kateřina Muñoz-Bonilla, Alexandra Měřinská, Dagmar Rybková, Zuzana Fernández-García, Marta Plachá, Daniela |
author_sort | Škrlová, Kateřina |
collection | PubMed |
description | Biodegradable polymers are promising materials for use in medical applications such as stents. Their properties are comparable to commercially available resistant metal and polymeric stents, which have several major problems, such as stent migration and stent clogging due to microbial biofilm. Consequently, conventional stents have to be removed operatively from the patient’s body, which presents a number of complications and can also endanger the patient’s life. Biodegradable stents disintegrate into basic substances that decompose in the human body, and no surgery is required. This review focuses on the specific use of stents in the human body, the problems of microbial biofilm, and possibilities of preventing microbial growth by modifying polymers with antimicrobial agents. |
format | Online Article Text |
id | pubmed-6915381 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-69153812019-12-24 Biocompatible Polymer Materials with Antimicrobial Properties for Preparation of Stents Škrlová, Kateřina Malachová, Kateřina Muñoz-Bonilla, Alexandra Měřinská, Dagmar Rybková, Zuzana Fernández-García, Marta Plachá, Daniela Nanomaterials (Basel) Review Biodegradable polymers are promising materials for use in medical applications such as stents. Their properties are comparable to commercially available resistant metal and polymeric stents, which have several major problems, such as stent migration and stent clogging due to microbial biofilm. Consequently, conventional stents have to be removed operatively from the patient’s body, which presents a number of complications and can also endanger the patient’s life. Biodegradable stents disintegrate into basic substances that decompose in the human body, and no surgery is required. This review focuses on the specific use of stents in the human body, the problems of microbial biofilm, and possibilities of preventing microbial growth by modifying polymers with antimicrobial agents. MDPI 2019-10-31 /pmc/articles/PMC6915381/ /pubmed/31683612 http://dx.doi.org/10.3390/nano9111548 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Škrlová, Kateřina Malachová, Kateřina Muñoz-Bonilla, Alexandra Měřinská, Dagmar Rybková, Zuzana Fernández-García, Marta Plachá, Daniela Biocompatible Polymer Materials with Antimicrobial Properties for Preparation of Stents |
title | Biocompatible Polymer Materials with Antimicrobial Properties for Preparation of Stents |
title_full | Biocompatible Polymer Materials with Antimicrobial Properties for Preparation of Stents |
title_fullStr | Biocompatible Polymer Materials with Antimicrobial Properties for Preparation of Stents |
title_full_unstemmed | Biocompatible Polymer Materials with Antimicrobial Properties for Preparation of Stents |
title_short | Biocompatible Polymer Materials with Antimicrobial Properties for Preparation of Stents |
title_sort | biocompatible polymer materials with antimicrobial properties for preparation of stents |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915381/ https://www.ncbi.nlm.nih.gov/pubmed/31683612 http://dx.doi.org/10.3390/nano9111548 |
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