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Characterization of Patients with Allergic Rhinitis to Ragweed Pollen in Two Distinct Regions of Romania

Background and objectives: Ragweed pollen is a major source of allergen, which has rarely been observed in Romania until now. In this study, we evaluated the symptoms and associated factors in patients with allergic rhinitis to ragweed pollen in two distinct regions of Romania. Materials and Methods...

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Autores principales: Bocsan, Ioana Corina, Muntean, Ioana Adriana, Ureche, Corina, Pop, Raluca Maria, Neag, Maria Adriana, Sabin, Octavia, Deleanu, Diana, Buzoianu, Anca Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915510/
https://www.ncbi.nlm.nih.gov/pubmed/31653048
http://dx.doi.org/10.3390/medicina55110712
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author Bocsan, Ioana Corina
Muntean, Ioana Adriana
Ureche, Corina
Pop, Raluca Maria
Neag, Maria Adriana
Sabin, Octavia
Deleanu, Diana
Buzoianu, Anca Dana
author_facet Bocsan, Ioana Corina
Muntean, Ioana Adriana
Ureche, Corina
Pop, Raluca Maria
Neag, Maria Adriana
Sabin, Octavia
Deleanu, Diana
Buzoianu, Anca Dana
author_sort Bocsan, Ioana Corina
collection PubMed
description Background and objectives: Ragweed pollen is a major source of allergen, which has rarely been observed in Romania until now. In this study, we evaluated the symptoms and associated factors in patients with allergic rhinitis to ragweed pollen in two distinct regions of Romania. Materials and Methods: We evaluated the records of patients newly diagnosed with allergic rhinitis induced by ragweed pollen in two allergological centers from North-West (NW) and Central parts of Romania between 2013 and 2015. The patients were clinically evaluated regarding disease length, presence, and severity of the allergic rhinitis symptoms and the association with other allergic manifestations (asthma and conjunctivitis). Results: The sensitization to ragweed was significantly higher in the NW part compared to the Central part (18.27% vs 4.1%, p < 0.001). More patients with monosensitization to ragweed pollen were observed in the NE center (27%) compared to the Central one (20.7%). Patients with monosensitization to ragweed pollen presented more severe forms of rhinitis (70% vs 31.5%, p = 0.02) in the NW part compared to polysensitized patients. The total symptoms score was significantly higher in patients from the Central part compared to the NW part (9.21 ± 2.01 vs 5.76 ±1.96, p < 0.001). Bronchial asthma was associated at a similar frequency to allergic rhinitis in both centers, but it was more frequently observed in monosensitized patients in the NW center. Allergic conjunctivitis was more frequently reported by patients from the Central part (75.86 vs 41.9, p = 0.02), while in the NW region it was noticed more commonly in monosensitized patients (65% vs 33.33, p = 0.02). Conclusions: Allergic rhinitis to ragweed pollen has been more frequently reported in the NW part of Romania. Patients with severe forms of rhinitis were observed in the central part, while in the NW the severe forms of disease were reported by patients with monosensitization. Ragweed pollen is intensely allergogenic and determines association of ocular and asthma symptoms. Co-sensitization increases the risk of asthma association.
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spelling pubmed-69155102019-12-24 Characterization of Patients with Allergic Rhinitis to Ragweed Pollen in Two Distinct Regions of Romania Bocsan, Ioana Corina Muntean, Ioana Adriana Ureche, Corina Pop, Raluca Maria Neag, Maria Adriana Sabin, Octavia Deleanu, Diana Buzoianu, Anca Dana Medicina (Kaunas) Article Background and objectives: Ragweed pollen is a major source of allergen, which has rarely been observed in Romania until now. In this study, we evaluated the symptoms and associated factors in patients with allergic rhinitis to ragweed pollen in two distinct regions of Romania. Materials and Methods: We evaluated the records of patients newly diagnosed with allergic rhinitis induced by ragweed pollen in two allergological centers from North-West (NW) and Central parts of Romania between 2013 and 2015. The patients were clinically evaluated regarding disease length, presence, and severity of the allergic rhinitis symptoms and the association with other allergic manifestations (asthma and conjunctivitis). Results: The sensitization to ragweed was significantly higher in the NW part compared to the Central part (18.27% vs 4.1%, p < 0.001). More patients with monosensitization to ragweed pollen were observed in the NE center (27%) compared to the Central one (20.7%). Patients with monosensitization to ragweed pollen presented more severe forms of rhinitis (70% vs 31.5%, p = 0.02) in the NW part compared to polysensitized patients. The total symptoms score was significantly higher in patients from the Central part compared to the NW part (9.21 ± 2.01 vs 5.76 ±1.96, p < 0.001). Bronchial asthma was associated at a similar frequency to allergic rhinitis in both centers, but it was more frequently observed in monosensitized patients in the NW center. Allergic conjunctivitis was more frequently reported by patients from the Central part (75.86 vs 41.9, p = 0.02), while in the NW region it was noticed more commonly in monosensitized patients (65% vs 33.33, p = 0.02). Conclusions: Allergic rhinitis to ragweed pollen has been more frequently reported in the NW part of Romania. Patients with severe forms of rhinitis were observed in the central part, while in the NW the severe forms of disease were reported by patients with monosensitization. Ragweed pollen is intensely allergogenic and determines association of ocular and asthma symptoms. Co-sensitization increases the risk of asthma association. MDPI 2019-10-24 /pmc/articles/PMC6915510/ /pubmed/31653048 http://dx.doi.org/10.3390/medicina55110712 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bocsan, Ioana Corina
Muntean, Ioana Adriana
Ureche, Corina
Pop, Raluca Maria
Neag, Maria Adriana
Sabin, Octavia
Deleanu, Diana
Buzoianu, Anca Dana
Characterization of Patients with Allergic Rhinitis to Ragweed Pollen in Two Distinct Regions of Romania
title Characterization of Patients with Allergic Rhinitis to Ragweed Pollen in Two Distinct Regions of Romania
title_full Characterization of Patients with Allergic Rhinitis to Ragweed Pollen in Two Distinct Regions of Romania
title_fullStr Characterization of Patients with Allergic Rhinitis to Ragweed Pollen in Two Distinct Regions of Romania
title_full_unstemmed Characterization of Patients with Allergic Rhinitis to Ragweed Pollen in Two Distinct Regions of Romania
title_short Characterization of Patients with Allergic Rhinitis to Ragweed Pollen in Two Distinct Regions of Romania
title_sort characterization of patients with allergic rhinitis to ragweed pollen in two distinct regions of romania
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915510/
https://www.ncbi.nlm.nih.gov/pubmed/31653048
http://dx.doi.org/10.3390/medicina55110712
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