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Either Rap1 or Cdc13 can protect telomeric single-stranded 3′ overhangs from degradation in vitro
Telomeres, the DNA-protein structures capping the ends of linear chromosomes, are important for regulating replicative senescence and maintaining genome stability. Telomeres consist of G-rich repetitive sequences that end in a G-rich single-stranded (ss) 3′ overhang, which is vital for telomere func...
Autores principales: | Runnberg, Rikard, Narayanan, Saishyam, Itriago, Humberto, Cohn, Marita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915718/ https://www.ncbi.nlm.nih.gov/pubmed/31844093 http://dx.doi.org/10.1038/s41598-019-55482-3 |
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