Cargando…
Primary cilia mediate mitochondrial stress responses to promote dopamine neuron survival in a Parkinson’s disease model
A primary cilium is an antenna-like structure on the cell surface that plays a crucial role in sensory perception and signal transduction. Mitochondria, the ‘powerhouse’ of the cell, control cell survival, and death. The cellular ability to remove dysfunctional mitochondria through mitophagy is impo...
Autores principales: | Bae, Ji-Eun, Kang, Gil Myung, Min, Se Hee, Jo, Doo Sin, Jung, Yong-Keun, Kim, Keetae, Kim, Min-Seon, Cho, Dong-Hyung |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915731/ https://www.ncbi.nlm.nih.gov/pubmed/31844040 http://dx.doi.org/10.1038/s41419-019-2184-y |
Ejemplares similares
-
Autophagy Regulates Formation of Primary Cilia in Mefloquine-Treated Cells
por: Shin, Ji Hyun, et al.
Publicado: (2015) -
Increased O-GlcNAcylation of Drp1 by amyloid-beta promotes mitochondrial fission and dysfunction in neuronal cells
por: Park, So Jung, et al.
Publicado: (2021) -
Mechanisms of Weight Control by Primary Cilia
por: Lee, Chan Hee, et al.
Publicado: (2022) -
O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease
por: Lee, Byeong Eun, et al.
Publicado: (2020) -
PLCγ1 in dopamine neurons critically regulates striatal dopamine release via VMAT2 and synapsin III
por: Kim, Hye Yun, et al.
Publicado: (2023)