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Towards Rational Computational Engineering of Psychrophilic Enzymes

Cold-adapted enzymes from psychrophilic species achieve their high catalytic efficiency at low temperature by a different partitioning of the activation free energy into its enthalpic and entropic components, compared to orthologous mesophilic enzymes. Their lower activation enthalpy, partly compens...

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Detalles Bibliográficos
Autores principales:	Sočan, Jaka, Isaksen, Geir Villy, Brandsdal, Bjørn Olav, Åqvist, Johan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915740/ https://www.ncbi.nlm.nih.gov/pubmed/31844096 http://dx.doi.org/10.1038/s41598-019-55697-4

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