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Effective and Rapid Generation of Functional Neutrophils from Induced Pluripotent Stem Cells Using ETV2-Modified mRNA
Human induced pluripotent stem cells (hiPSCs) can serve as a versatile and scalable source of neutrophils for biomedical research and transfusion therapies. Here we describe a rapid efficient serum- and xenogen-free protocol for neutrophil generation, which is based on direct hematoendothelial progr...
Autores principales: | Brok-Volchanskaya, Vera S., Bennin, David A., Suknuntha, Kran, Klemm, Lucas C., Huttenlocher, Anna, Slukvin, Igor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915846/ https://www.ncbi.nlm.nih.gov/pubmed/31708474 http://dx.doi.org/10.1016/j.stemcr.2019.10.007 |
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