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The impact of inclusion, dose and duration of pyrazinamide (PZA) on efficacy and safety outcomes in tuberculosis: systematic review and meta-analysis protocol

BACKGROUND: Pyrazinamide (PZA) is a key component of current and future regimens for tuberculosis (TB). Inclusion of PZA at higher doses and for longer durations may improve efficacy outcomes but must be balanced against the potential for worse safety outcomes. METHODS: We will search for randomised...

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Detalles Bibliográficos
Autores principales: Millard, James D., Mackay, Elizabeth A., Bonnett, Laura J., Davies, Geraint R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915872/
https://www.ncbi.nlm.nih.gov/pubmed/31847921
http://dx.doi.org/10.1186/s13643-019-1231-1