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Do functional changes occur in the bladder due to bladder outlet obstruction? ‐ ICI‐RS 2018

Studies on bladder dysfunction (BD), more specifically functional‐urodynamic changes in the bladder as a result of bladder outlet obstruction (BOO) have been summarized for this TT. Based on available, but limited evidence from human studies a three‐stage model can be hypothesized to characterize BO...

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Detalles Bibliográficos
Autores principales: Bosch, Ruud, Abrams, Paul, Averbeck, Marcio Augusto, Finazzi Agró, Enrico, Gammie, Andrew, Marcelissen, Tom, Solomon, Eskinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915908/
https://www.ncbi.nlm.nih.gov/pubmed/31278801
http://dx.doi.org/10.1002/nau.24076
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author Bosch, Ruud
Abrams, Paul
Averbeck, Marcio Augusto
Finazzi Agró, Enrico
Gammie, Andrew
Marcelissen, Tom
Solomon, Eskinder
author_facet Bosch, Ruud
Abrams, Paul
Averbeck, Marcio Augusto
Finazzi Agró, Enrico
Gammie, Andrew
Marcelissen, Tom
Solomon, Eskinder
author_sort Bosch, Ruud
collection PubMed
description Studies on bladder dysfunction (BD), more specifically functional‐urodynamic changes in the bladder as a result of bladder outlet obstruction (BOO) have been summarized for this TT. Based on available, but limited evidence from human studies a three‐stage model can be hypothesized to characterize BOO‐induced bladder remodeling: hypertrophy, compensation (increased detrusor contractility during the voiding phase, often in combination with filling phase detrusor overactivity) followed by the phase of decompensation [detrusor underactivity]. The time between the start of compensation and eventual decompensation seems to be determined by age of onset, severity, and type of obstruction and clinical mitigating factors such as vascular and metabolic problems. Understanding the relative contributions of these factors may allow the development of personalized timelines and probabilities for these obstructed patients.
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spelling pubmed-69159082019-12-17 Do functional changes occur in the bladder due to bladder outlet obstruction? ‐ ICI‐RS 2018 Bosch, Ruud Abrams, Paul Averbeck, Marcio Augusto Finazzi Agró, Enrico Gammie, Andrew Marcelissen, Tom Solomon, Eskinder Neurourol Urodyn Review Articles Studies on bladder dysfunction (BD), more specifically functional‐urodynamic changes in the bladder as a result of bladder outlet obstruction (BOO) have been summarized for this TT. Based on available, but limited evidence from human studies a three‐stage model can be hypothesized to characterize BOO‐induced bladder remodeling: hypertrophy, compensation (increased detrusor contractility during the voiding phase, often in combination with filling phase detrusor overactivity) followed by the phase of decompensation [detrusor underactivity]. The time between the start of compensation and eventual decompensation seems to be determined by age of onset, severity, and type of obstruction and clinical mitigating factors such as vascular and metabolic problems. Understanding the relative contributions of these factors may allow the development of personalized timelines and probabilities for these obstructed patients. John Wiley and Sons Inc. 2019-07-06 2019-12 /pmc/articles/PMC6915908/ /pubmed/31278801 http://dx.doi.org/10.1002/nau.24076 Text en © 2019 The Authors. Neurourology and Urodynamics Published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Articles
Bosch, Ruud
Abrams, Paul
Averbeck, Marcio Augusto
Finazzi Agró, Enrico
Gammie, Andrew
Marcelissen, Tom
Solomon, Eskinder
Do functional changes occur in the bladder due to bladder outlet obstruction? ‐ ICI‐RS 2018
title Do functional changes occur in the bladder due to bladder outlet obstruction? ‐ ICI‐RS 2018
title_full Do functional changes occur in the bladder due to bladder outlet obstruction? ‐ ICI‐RS 2018
title_fullStr Do functional changes occur in the bladder due to bladder outlet obstruction? ‐ ICI‐RS 2018
title_full_unstemmed Do functional changes occur in the bladder due to bladder outlet obstruction? ‐ ICI‐RS 2018
title_short Do functional changes occur in the bladder due to bladder outlet obstruction? ‐ ICI‐RS 2018
title_sort do functional changes occur in the bladder due to bladder outlet obstruction? ‐ ici‐rs 2018
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915908/
https://www.ncbi.nlm.nih.gov/pubmed/31278801
http://dx.doi.org/10.1002/nau.24076
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