Cargando…
Do functional changes occur in the bladder due to bladder outlet obstruction? ‐ ICI‐RS 2018
Studies on bladder dysfunction (BD), more specifically functional‐urodynamic changes in the bladder as a result of bladder outlet obstruction (BOO) have been summarized for this TT. Based on available, but limited evidence from human studies a three‐stage model can be hypothesized to characterize BO...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915908/ https://www.ncbi.nlm.nih.gov/pubmed/31278801 http://dx.doi.org/10.1002/nau.24076 |
_version_ | 1783480119987273728 |
---|---|
author | Bosch, Ruud Abrams, Paul Averbeck, Marcio Augusto Finazzi Agró, Enrico Gammie, Andrew Marcelissen, Tom Solomon, Eskinder |
author_facet | Bosch, Ruud Abrams, Paul Averbeck, Marcio Augusto Finazzi Agró, Enrico Gammie, Andrew Marcelissen, Tom Solomon, Eskinder |
author_sort | Bosch, Ruud |
collection | PubMed |
description | Studies on bladder dysfunction (BD), more specifically functional‐urodynamic changes in the bladder as a result of bladder outlet obstruction (BOO) have been summarized for this TT. Based on available, but limited evidence from human studies a three‐stage model can be hypothesized to characterize BOO‐induced bladder remodeling: hypertrophy, compensation (increased detrusor contractility during the voiding phase, often in combination with filling phase detrusor overactivity) followed by the phase of decompensation [detrusor underactivity]. The time between the start of compensation and eventual decompensation seems to be determined by age of onset, severity, and type of obstruction and clinical mitigating factors such as vascular and metabolic problems. Understanding the relative contributions of these factors may allow the development of personalized timelines and probabilities for these obstructed patients. |
format | Online Article Text |
id | pubmed-6915908 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-69159082019-12-17 Do functional changes occur in the bladder due to bladder outlet obstruction? ‐ ICI‐RS 2018 Bosch, Ruud Abrams, Paul Averbeck, Marcio Augusto Finazzi Agró, Enrico Gammie, Andrew Marcelissen, Tom Solomon, Eskinder Neurourol Urodyn Review Articles Studies on bladder dysfunction (BD), more specifically functional‐urodynamic changes in the bladder as a result of bladder outlet obstruction (BOO) have been summarized for this TT. Based on available, but limited evidence from human studies a three‐stage model can be hypothesized to characterize BOO‐induced bladder remodeling: hypertrophy, compensation (increased detrusor contractility during the voiding phase, often in combination with filling phase detrusor overactivity) followed by the phase of decompensation [detrusor underactivity]. The time between the start of compensation and eventual decompensation seems to be determined by age of onset, severity, and type of obstruction and clinical mitigating factors such as vascular and metabolic problems. Understanding the relative contributions of these factors may allow the development of personalized timelines and probabilities for these obstructed patients. John Wiley and Sons Inc. 2019-07-06 2019-12 /pmc/articles/PMC6915908/ /pubmed/31278801 http://dx.doi.org/10.1002/nau.24076 Text en © 2019 The Authors. Neurourology and Urodynamics Published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Articles Bosch, Ruud Abrams, Paul Averbeck, Marcio Augusto Finazzi Agró, Enrico Gammie, Andrew Marcelissen, Tom Solomon, Eskinder Do functional changes occur in the bladder due to bladder outlet obstruction? ‐ ICI‐RS 2018 |
title | Do functional changes occur in the bladder due to bladder outlet obstruction? ‐ ICI‐RS 2018 |
title_full | Do functional changes occur in the bladder due to bladder outlet obstruction? ‐ ICI‐RS 2018 |
title_fullStr | Do functional changes occur in the bladder due to bladder outlet obstruction? ‐ ICI‐RS 2018 |
title_full_unstemmed | Do functional changes occur in the bladder due to bladder outlet obstruction? ‐ ICI‐RS 2018 |
title_short | Do functional changes occur in the bladder due to bladder outlet obstruction? ‐ ICI‐RS 2018 |
title_sort | do functional changes occur in the bladder due to bladder outlet obstruction? ‐ ici‐rs 2018 |
topic | Review Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915908/ https://www.ncbi.nlm.nih.gov/pubmed/31278801 http://dx.doi.org/10.1002/nau.24076 |
work_keys_str_mv | AT boschruud dofunctionalchangesoccurinthebladderduetobladderoutletobstructionicirs2018 AT abramspaul dofunctionalchangesoccurinthebladderduetobladderoutletobstructionicirs2018 AT averbeckmarcioaugusto dofunctionalchangesoccurinthebladderduetobladderoutletobstructionicirs2018 AT finazziagroenrico dofunctionalchangesoccurinthebladderduetobladderoutletobstructionicirs2018 AT gammieandrew dofunctionalchangesoccurinthebladderduetobladderoutletobstructionicirs2018 AT marcelissentom dofunctionalchangesoccurinthebladderduetobladderoutletobstructionicirs2018 AT solomoneskinder dofunctionalchangesoccurinthebladderduetobladderoutletobstructionicirs2018 |