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NQO1 potentiates apoptosis evasion and upregulates XIAP via inhibiting proteasome-mediated degradation SIRT6 in hepatocellular carcinoma

BACKGROUND: Our previous study has demonstrated that NAD(P)H: quinone oxidoreductase 1 (NQO1) is significantly upregulated in human liver cancer where it potentiates the apoptosis evasion of liver cancer cell. However, the underlying mechanisms of the oncogenic function of NQO1 in HCC have not been...

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Detalles Bibliográficos
Autores principales:	Zhou, Hong-Zhong, Zeng, Han-Qing, Yuan, Ding, Ren, Ji-Hua, Cheng, Sheng-Tao, Yu, Hai-Bo, Ren, Fang, Wang, Qing, Qin, Yi-Ping, Huang, Ai-Long, Chen, Juan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915971/ https://www.ncbi.nlm.nih.gov/pubmed/31842909 http://dx.doi.org/10.1186/s12964-019-0491-7

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