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ROS as a novel indicator to predict anticancer drug efficacy

BACKGROUND: Mitochondria are considered a primary intracellular site of reactive oxygen species (ROS) generation. Generally, cancer cells with mitochondrial genetic abnormalities (copy number change and mutations) have escalated ROS levels compared to normal cells. Since high levels of ROS can trigg...

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Detalles Bibliográficos
Autores principales:	Zaidieh, Tarek, Smith, James R., Ball, Karen E., An, Qian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916036/ https://www.ncbi.nlm.nih.gov/pubmed/31842863 http://dx.doi.org/10.1186/s12885-019-6438-y

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