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Efficacy of chlorthalidone and hydrochlorothiazide in combination with amiloride in multiple doses on blood pressure in patients with primary hypertension: a protocol for a factorial randomized controlled trial

BACKGROUND: Thiazide diuretics have demonstrated favorable blood pressure lowering efficacy, but the equivalent doses of their more common agents, chlorthalidone and hydrochlorothiazide, are still unclear. Further, concerns exist regarding adverse metabolic effects, which may be attenuated with the...

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Detalles Bibliográficos
Autores principales:	Martins, Vítor Magnus, Helal, Lucas, Ferrari, Filipe, Bottino, Leonardo Grabinski, Fuchs, Sandra Costa, Fuchs, Flávio Danni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916111/ https://www.ncbi.nlm.nih.gov/pubmed/31843024 http://dx.doi.org/10.1186/s13063-019-3909-z

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