Population pharmacokinetics of piperacillin in febrile children receiving cancer chemotherapy: the impact of body weight and target on an optimal dosing regimen

BACKGROUND: The β-lactam antibiotic piperacillin (in combination with tazobactam) is commonly chosen for empirical treatment of suspected bacterial infections. However, pharmacokinetic variability among patient populations and across ages leads to uncertainty when selecting a dosing regimen to achie...

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Detalles Bibliográficos
Autores principales: Thorsted, Anders, Kristoffersson, Anders N, Maarbjerg, Sabine F, Schrøder, Henrik, Wang, Mikala, Brock, Birgitte, Nielsen, Elisabet I, Friberg, Lena E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916132/
https://www.ncbi.nlm.nih.gov/pubmed/31273375
http://dx.doi.org/10.1093/jac/dkz270

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