Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways, regulation DC/Treg induced immune tolerance and improving gut microecology

BACKGROUND: This study was to investigate the effect and its possible mechanism of fucoidan on the development of spontaneous autoimmune diabetes in non-obese diabetic (NOD) mice. METHODS: 7-week-old NOD mice were randomly divided into three groups: control group, low-dose (300 mg/kg) and high-dose...

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Detalles Bibliográficos
Autores principales: Xue, Meilan, Liang, Hui, Ji, Xinqiang, Liu, Ying, Ge, Yinlin, Hou, Lin, Sun, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916240/
https://www.ncbi.nlm.nih.gov/pubmed/31889967
http://dx.doi.org/10.1186/s12986-019-0392-1

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