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Oral ferroportin inhibitor VIT‐2763: First‐in‐human, phase 1 study in healthy volunteers
Restriction of iron availability by ferroportin inhibition is a novel approach to treating non‐transfusion‐dependent thalassemia (β‐thalassemia intermedia). This first‐in‐human, Phase I study (https://www.clinicaltrialsregister.eu; EudraCT no. 2017‐003395‐31) assessed the safety, tolerability, pharm...
Autores principales: | Richard, Frank, van Lier, Jan Jaap, Roubert, Bernard, Haboubi, Teba, Göhring, Udo‐Michael, Dürrenberger, Franz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916274/ https://www.ncbi.nlm.nih.gov/pubmed/31674058 http://dx.doi.org/10.1002/ajh.25670 |
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