Differential contribution of education through KIR2DL1, KIR2DL3, and KIR3DL1 to antibody‐dependent (AD) NK cell activation and ADCC

The engagement of activating NK receptors (aNKR) stimulates NK cell activity, provided that interactions between inhibitory NK receptors (iNKR) with their HLA ligands do not override them. Abs bound to target cells can also activate NK cells by engaging the CD16 aNKR. NK cell education status is an...

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Detalles Bibliográficos
Autores principales: Lisovsky, Irene, Kant, Sanket, Tremblay‐McLean, Alexandra, Isitman, Gamze, Kiani, Zahra, Dupuy, Franck P., Gilbert, Louise, Bruneau, Julie, Shoukry, Naglaa H., Lebouché, Bertrand, Bernard, Nicole F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Host Defense & Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916277/
https://www.ncbi.nlm.nih.gov/pubmed/30698860
http://dx.doi.org/10.1002/JLB.4A0617-242RRR

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