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Imaging of translocator protein upregulation is selective for pro‐inflammatory polarized astrocytes and microglia
Translocator protein (TSPO) expression is increased in activated glia, and has been used as a marker of neuroinflammation in PET imaging. However, the extent to which TSPO upregulation reflects a pro‐ or anti‐inflammatory phenotype remains unclear. Our aim was to determine whether TSPO upregulation...
Autores principales: | Pannell, Maria, Economopoulos, Vasiliki, Wilson, Thomas C., Kersemans, Veerle, Isenegger, Patrick G., Larkin, James R., Smart, Sean, Gilchrist, Stuart, Gouverneur, Véronique, Sibson, Nicola R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916298/ https://www.ncbi.nlm.nih.gov/pubmed/31479168 http://dx.doi.org/10.1002/glia.23716 |
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