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Fusion transcripts: Unexploited vulnerabilities in cancer?

Gene fusions are an important class of mutations in several cancer types and include genomic rearrangements that fuse regulatory or coding elements from two different genes. Analysis of the genetics of cancers harboring fusion oncogenes and the proteins they encode have enhanced cancer diagnosis and...

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Detalles Bibliográficos
Autores principales: Neckles, Carla, Sundara Rajan, Soumya, Caplen, Natasha J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916338/
https://www.ncbi.nlm.nih.gov/pubmed/31407506
http://dx.doi.org/10.1002/wrna.1562