Single‐cell study of neural stem cells derived from human iPSCs reveals distinct progenitor populations with neurogenic and gliogenic potential

We used single‐cell RNA sequencing (seq) on several human induced pluripotent stem (iPS) cell‐derived neural stem cell (NSC) lines and one fetal brain‐derived NSC line to study inherent cell type heterogeneity at proliferating neural stem cell stage and uncovered predisposed presence of neurogenic a...

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Detalles Bibliográficos
Autores principales: Lam, Matti, Sanosaka, Tsukasa, Lundin, Anders, Imaizumi, Kent, Etal, Damla, Karlsson, Fredrik H., Clausen, Maryam, Cairns, Jonathan, Hicks, Ryan, Kohyama, Jun, Kele, Malin, Okano, Hideyuki, Falk, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916357/
https://www.ncbi.nlm.nih.gov/pubmed/31651061
http://dx.doi.org/10.1111/gtc.12731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916357/
https://www.ncbi.nlm.nih.gov/pubmed/31651061
http://dx.doi.org/10.1111/gtc.12731

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