Visible‐Light‐Driven Intermolecular Reductive Ene–Yne Coupling by Iridium/Cobalt Dual Catalysis for C(sp(3))−C(sp(2)) Bond Formation

A new methodology to form C(sp(3))−C(sp(2)) bonds by visible‐light‐driven intermolecular reductive ene–yne coupling has been successfully developed. The process relies on the ability of the Hantzsch ester to contribute in both SET and HAT processes through a unified cobalt and iridium catalytic syst...

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Detalles Bibliográficos
Autores principales: González, María J., Breit, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916364/
https://www.ncbi.nlm.nih.gov/pubmed/31549749
http://dx.doi.org/10.1002/chem.201903708
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author González, María J.
Breit, Bernhard
author_facet González, María J.
Breit, Bernhard
author_sort González, María J.
collection PubMed
description A new methodology to form C(sp(3))−C(sp(2)) bonds by visible‐light‐driven intermolecular reductive ene–yne coupling has been successfully developed. The process relies on the ability of the Hantzsch ester to contribute in both SET and HAT processes through a unified cobalt and iridium catalytic system. This procedure avoids the use of stoichiometric amounts of reducing metallic reagents, which is translated into high functional‐group tolerance and atom economy.
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spelling pubmed-69163642019-12-17 Visible‐Light‐Driven Intermolecular Reductive Ene–Yne Coupling by Iridium/Cobalt Dual Catalysis for C(sp(3))−C(sp(2)) Bond Formation González, María J. Breit, Bernhard Chemistry Communications A new methodology to form C(sp(3))−C(sp(2)) bonds by visible‐light‐driven intermolecular reductive ene–yne coupling has been successfully developed. The process relies on the ability of the Hantzsch ester to contribute in both SET and HAT processes through a unified cobalt and iridium catalytic system. This procedure avoids the use of stoichiometric amounts of reducing metallic reagents, which is translated into high functional‐group tolerance and atom economy. John Wiley and Sons Inc. 2019-11-08 2019-12-10 /pmc/articles/PMC6916364/ /pubmed/31549749 http://dx.doi.org/10.1002/chem.201903708 Text en © 2019 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Communications
González, María J.
Breit, Bernhard
Visible‐Light‐Driven Intermolecular Reductive Ene–Yne Coupling by Iridium/Cobalt Dual Catalysis for C(sp(3))−C(sp(2)) Bond Formation
title Visible‐Light‐Driven Intermolecular Reductive Ene–Yne Coupling by Iridium/Cobalt Dual Catalysis for C(sp(3))−C(sp(2)) Bond Formation
title_full Visible‐Light‐Driven Intermolecular Reductive Ene–Yne Coupling by Iridium/Cobalt Dual Catalysis for C(sp(3))−C(sp(2)) Bond Formation
title_fullStr Visible‐Light‐Driven Intermolecular Reductive Ene–Yne Coupling by Iridium/Cobalt Dual Catalysis for C(sp(3))−C(sp(2)) Bond Formation
title_full_unstemmed Visible‐Light‐Driven Intermolecular Reductive Ene–Yne Coupling by Iridium/Cobalt Dual Catalysis for C(sp(3))−C(sp(2)) Bond Formation
title_short Visible‐Light‐Driven Intermolecular Reductive Ene–Yne Coupling by Iridium/Cobalt Dual Catalysis for C(sp(3))−C(sp(2)) Bond Formation
title_sort visible‐light‐driven intermolecular reductive ene–yne coupling by iridium/cobalt dual catalysis for c(sp(3))−c(sp(2)) bond formation
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916364/
https://www.ncbi.nlm.nih.gov/pubmed/31549749
http://dx.doi.org/10.1002/chem.201903708
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