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DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models
BACKGROUND: Systemic sclerosis is a multisystem inflammatory and vascular lesion leading to extensive tissue fibrosis. A reversible S-adenosyl-l-homocysteine hydrolase (SAHH) inhibitor, DZ2002, modulates the pathologic processes of various inflammatory diseases and autoimmune diseases. This study is...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916442/ https://www.ncbi.nlm.nih.gov/pubmed/31842999 http://dx.doi.org/10.1186/s13075-019-2074-9 |