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PRC1 promotes GLI1-dependent osteopontin expression in association with the Wnt/β-catenin signaling pathway and aggravates liver fibrosis

BACKGROUND: PRC1 (Protein regulator of cytokinesis 1) regulates microtubules organization and functions as a novel regulator in Wnt/β-catenin signaling pathway. Wnt/β-catenin is involved in development of liver fibrosis (LF). We aim to investigate effect and mechanism of PRC1 on liver fibrosis. METH...

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Detalles Bibliográficos
Autores principales:	Rao, Shenzong, Xiang, Jie, Huang, Jingsong, Zhang, Shangang, Zhang, Min, Sun, Haoran, Li, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916466/ https://www.ncbi.nlm.nih.gov/pubmed/31867100 http://dx.doi.org/10.1186/s13578-019-0363-2

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