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Acceptability and safety of thermal ablation for the treatment of precancerous cervical lesions in Honduras
OBJECTIVE: To evaluate the acceptability and safety of thermal ablation (TA) for the treatment of precancerous cervical lesions in women in Honduras. METHODS: Human papillomavirus (HPV) and visual inspection with acetic acid (VIA) screen‐positive eligible women received TA. After treatment, women ra...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916631/ https://www.ncbi.nlm.nih.gov/pubmed/31622526 http://dx.doi.org/10.1111/tmi.13315 |
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author | Sandoval, Manuel Slavkovsky, Rose Bansil, Pooja Jeronimo, Jose Lim, Jeanette Figueroa, Jacqueline de Sanjose, Silvia |
author_facet | Sandoval, Manuel Slavkovsky, Rose Bansil, Pooja Jeronimo, Jose Lim, Jeanette Figueroa, Jacqueline de Sanjose, Silvia |
author_sort | Sandoval, Manuel |
collection | PubMed |
description | OBJECTIVE: To evaluate the acceptability and safety of thermal ablation (TA) for the treatment of precancerous cervical lesions in women in Honduras. METHODS: Human papillomavirus (HPV) and visual inspection with acetic acid (VIA) screen‐positive eligible women received TA. After treatment, women rated the level of pain experienced during treatment using the Wong‐Baker FACES® pain‐rating scale from 0 to 10. Short‐term safety outcomes that could require medical attention were assessed one month after treatment. RESULTS: A total of 319 women received TA treatment. The average pain rating was 2.5 (95% CI: 2.3–2.8), and 85% rated their pain levels as less than 6. No significant differences in low (below 6) or high (6 and above) pain were found by age or number of biopsies performed, but there was a significant difference by the number of TA applications (P < 0.01). When asked if they would recommend this treatment, all women said they would. At the one‐month follow‐up visit, the most common reported discomforts were bleeding (10%) and cramping (8.4%); 11 women reported severe lower abdominal pain, and none required medical attention. CONCLUSIONS: TA is safe and acceptable to patients as a treatment option for precancerous cervical lesions in low‐resource settings. |
format | Online Article Text |
id | pubmed-6916631 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-69166312019-12-23 Acceptability and safety of thermal ablation for the treatment of precancerous cervical lesions in Honduras Sandoval, Manuel Slavkovsky, Rose Bansil, Pooja Jeronimo, Jose Lim, Jeanette Figueroa, Jacqueline de Sanjose, Silvia Trop Med Int Health Editors' Choice OBJECTIVE: To evaluate the acceptability and safety of thermal ablation (TA) for the treatment of precancerous cervical lesions in women in Honduras. METHODS: Human papillomavirus (HPV) and visual inspection with acetic acid (VIA) screen‐positive eligible women received TA. After treatment, women rated the level of pain experienced during treatment using the Wong‐Baker FACES® pain‐rating scale from 0 to 10. Short‐term safety outcomes that could require medical attention were assessed one month after treatment. RESULTS: A total of 319 women received TA treatment. The average pain rating was 2.5 (95% CI: 2.3–2.8), and 85% rated their pain levels as less than 6. No significant differences in low (below 6) or high (6 and above) pain were found by age or number of biopsies performed, but there was a significant difference by the number of TA applications (P < 0.01). When asked if they would recommend this treatment, all women said they would. At the one‐month follow‐up visit, the most common reported discomforts were bleeding (10%) and cramping (8.4%); 11 women reported severe lower abdominal pain, and none required medical attention. CONCLUSIONS: TA is safe and acceptable to patients as a treatment option for precancerous cervical lesions in low‐resource settings. John Wiley and Sons Inc. 2019-11-21 2019-12 /pmc/articles/PMC6916631/ /pubmed/31622526 http://dx.doi.org/10.1111/tmi.13315 Text en © 2019 The Authors. Tropical Medicine & International Health Published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Editors' Choice Sandoval, Manuel Slavkovsky, Rose Bansil, Pooja Jeronimo, Jose Lim, Jeanette Figueroa, Jacqueline de Sanjose, Silvia Acceptability and safety of thermal ablation for the treatment of precancerous cervical lesions in Honduras |
title | Acceptability and safety of thermal ablation for the treatment of precancerous cervical lesions in Honduras |
title_full | Acceptability and safety of thermal ablation for the treatment of precancerous cervical lesions in Honduras |
title_fullStr | Acceptability and safety of thermal ablation for the treatment of precancerous cervical lesions in Honduras |
title_full_unstemmed | Acceptability and safety of thermal ablation for the treatment of precancerous cervical lesions in Honduras |
title_short | Acceptability and safety of thermal ablation for the treatment of precancerous cervical lesions in Honduras |
title_sort | acceptability and safety of thermal ablation for the treatment of precancerous cervical lesions in honduras |
topic | Editors' Choice |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916631/ https://www.ncbi.nlm.nih.gov/pubmed/31622526 http://dx.doi.org/10.1111/tmi.13315 |
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