Cargando…

Acceptability and safety of thermal ablation for the treatment of precancerous cervical lesions in Honduras

OBJECTIVE: To evaluate the acceptability and safety of thermal ablation (TA) for the treatment of precancerous cervical lesions in women in Honduras. METHODS: Human papillomavirus (HPV) and visual inspection with acetic acid (VIA) screen‐positive eligible women received TA. After treatment, women ra...

Descripción completa

Detalles Bibliográficos
Autores principales: Sandoval, Manuel, Slavkovsky, Rose, Bansil, Pooja, Jeronimo, Jose, Lim, Jeanette, Figueroa, Jacqueline, de Sanjose, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916631/
https://www.ncbi.nlm.nih.gov/pubmed/31622526
http://dx.doi.org/10.1111/tmi.13315
_version_ 1783480272388358144
author Sandoval, Manuel
Slavkovsky, Rose
Bansil, Pooja
Jeronimo, Jose
Lim, Jeanette
Figueroa, Jacqueline
de Sanjose, Silvia
author_facet Sandoval, Manuel
Slavkovsky, Rose
Bansil, Pooja
Jeronimo, Jose
Lim, Jeanette
Figueroa, Jacqueline
de Sanjose, Silvia
author_sort Sandoval, Manuel
collection PubMed
description OBJECTIVE: To evaluate the acceptability and safety of thermal ablation (TA) for the treatment of precancerous cervical lesions in women in Honduras. METHODS: Human papillomavirus (HPV) and visual inspection with acetic acid (VIA) screen‐positive eligible women received TA. After treatment, women rated the level of pain experienced during treatment using the Wong‐Baker FACES® pain‐rating scale from 0 to 10. Short‐term safety outcomes that could require medical attention were assessed one month after treatment. RESULTS: A total of 319 women received TA treatment. The average pain rating was 2.5 (95% CI: 2.3–2.8), and 85% rated their pain levels as less than 6. No significant differences in low (below 6) or high (6 and above) pain were found by age or number of biopsies performed, but there was a significant difference by the number of TA applications (P < 0.01). When asked if they would recommend this treatment, all women said they would. At the one‐month follow‐up visit, the most common reported discomforts were bleeding (10%) and cramping (8.4%); 11 women reported severe lower abdominal pain, and none required medical attention. CONCLUSIONS: TA is safe and acceptable to patients as a treatment option for precancerous cervical lesions in low‐resource settings.
format Online
Article
Text
id pubmed-6916631
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-69166312019-12-23 Acceptability and safety of thermal ablation for the treatment of precancerous cervical lesions in Honduras Sandoval, Manuel Slavkovsky, Rose Bansil, Pooja Jeronimo, Jose Lim, Jeanette Figueroa, Jacqueline de Sanjose, Silvia Trop Med Int Health Editors' Choice OBJECTIVE: To evaluate the acceptability and safety of thermal ablation (TA) for the treatment of precancerous cervical lesions in women in Honduras. METHODS: Human papillomavirus (HPV) and visual inspection with acetic acid (VIA) screen‐positive eligible women received TA. After treatment, women rated the level of pain experienced during treatment using the Wong‐Baker FACES® pain‐rating scale from 0 to 10. Short‐term safety outcomes that could require medical attention were assessed one month after treatment. RESULTS: A total of 319 women received TA treatment. The average pain rating was 2.5 (95% CI: 2.3–2.8), and 85% rated their pain levels as less than 6. No significant differences in low (below 6) or high (6 and above) pain were found by age or number of biopsies performed, but there was a significant difference by the number of TA applications (P < 0.01). When asked if they would recommend this treatment, all women said they would. At the one‐month follow‐up visit, the most common reported discomforts were bleeding (10%) and cramping (8.4%); 11 women reported severe lower abdominal pain, and none required medical attention. CONCLUSIONS: TA is safe and acceptable to patients as a treatment option for precancerous cervical lesions in low‐resource settings. John Wiley and Sons Inc. 2019-11-21 2019-12 /pmc/articles/PMC6916631/ /pubmed/31622526 http://dx.doi.org/10.1111/tmi.13315 Text en © 2019 The Authors. Tropical Medicine & International Health Published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Editors' Choice
Sandoval, Manuel
Slavkovsky, Rose
Bansil, Pooja
Jeronimo, Jose
Lim, Jeanette
Figueroa, Jacqueline
de Sanjose, Silvia
Acceptability and safety of thermal ablation for the treatment of precancerous cervical lesions in Honduras
title Acceptability and safety of thermal ablation for the treatment of precancerous cervical lesions in Honduras
title_full Acceptability and safety of thermal ablation for the treatment of precancerous cervical lesions in Honduras
title_fullStr Acceptability and safety of thermal ablation for the treatment of precancerous cervical lesions in Honduras
title_full_unstemmed Acceptability and safety of thermal ablation for the treatment of precancerous cervical lesions in Honduras
title_short Acceptability and safety of thermal ablation for the treatment of precancerous cervical lesions in Honduras
title_sort acceptability and safety of thermal ablation for the treatment of precancerous cervical lesions in honduras
topic Editors' Choice
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916631/
https://www.ncbi.nlm.nih.gov/pubmed/31622526
http://dx.doi.org/10.1111/tmi.13315
work_keys_str_mv AT sandovalmanuel acceptabilityandsafetyofthermalablationforthetreatmentofprecancerouscervicallesionsinhonduras
AT slavkovskyrose acceptabilityandsafetyofthermalablationforthetreatmentofprecancerouscervicallesionsinhonduras
AT bansilpooja acceptabilityandsafetyofthermalablationforthetreatmentofprecancerouscervicallesionsinhonduras
AT jeronimojose acceptabilityandsafetyofthermalablationforthetreatmentofprecancerouscervicallesionsinhonduras
AT limjeanette acceptabilityandsafetyofthermalablationforthetreatmentofprecancerouscervicallesionsinhonduras
AT figueroajacqueline acceptabilityandsafetyofthermalablationforthetreatmentofprecancerouscervicallesionsinhonduras
AT desanjosesilvia acceptabilityandsafetyofthermalablationforthetreatmentofprecancerouscervicallesionsinhonduras