Bcl2‐Expressing Quiescent Type B Neural Stem Cells in the Ventricular–Subventricular Zone Are Resistant to Concurrent Temozolomide/X‐Irradiation

The ventricular–subventricular zone (V‐SVZ) of the mammalian brain is a site of adult neurogenesis. Within the V‐SVZ reside type B neural stem cells (NSCs) and type A neuroblasts. The V‐SVZ is also a primary site for very aggressive glioblastoma (GBM). Standard‐of‐care therapy for GBM consists of sa...

Descripción completa

Detalles Bibliográficos
Autores principales: Cameron, Brent D., Traver, Geri, Roland, Joseph T., Brockman, Asa A., Dean, Daniel, Johnson, Levi, Boyd, Kelli, Ihrie, Rebecca A., Freeman, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Translational and Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916634/
https://www.ncbi.nlm.nih.gov/pubmed/31430423
http://dx.doi.org/10.1002/stem.3081

Ejemplares similares

Ejemplares similares