CRISPR/Cas9‐Based Dystrophin Restoration Reveals a Novel Role for Dystrophin in Bioenergetics and Stress Resistance of Muscle Progenitors

Although the lack of dystrophin expression in muscle myofibers is the central cause of Duchenne muscular dystrophy (DMD), accumulating evidence suggests that DMD may also be a stem cell disease. Recent studies have revealed dystrophin expression in satellite cells and demonstrated that dystrophin de...

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Detalles Bibliográficos
Autores principales: Matre, Polina R., Mu, Xiaodong, Wu, Jianbo, Danila, Delia, Hall, Mary A., Kolonin, Mikhail G., Darabi, Radbod, Huard, Johnny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Tissue‐Specific Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916636/
https://www.ncbi.nlm.nih.gov/pubmed/31574188
http://dx.doi.org/10.1002/stem.3094

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