Cargando…

Synthesis of Novel Xanthone Analogues and Their Growth Inhibitory Activity Against Human Lung Cancer A549 Cells

PURPOSE: Xanthones demonstrated an array of pharmacological activities via non-covalent DNA interaction and have been widely utilized in new drug research. The introduction of the polar 1,2,3-triazole ring located at the C3-position of xanthone has not been reported thus far. METHODS: In the present...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Junqi, Dai, Jinwei, Zhang, Yuyang, Wang, Jing, Huang, Lei, Ding, Hongmei, Li, Tiejun, Zhang, Yuefan, Mao, Junqin, Yu, Shichong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916687/ https://www.ncbi.nlm.nih.gov/pubmed/31853172 http://dx.doi.org/10.2147/DDDT.S217827

Ejemplares similares

Xanthone Glucosides: Isolation, Bioactivity and Synthesis
por: Huang, Qing, et al.
Publicado: (2021)

Three New Xanthones from Hypericum scabrum and Their Quorum Sensing Inhibitory Activities against Chromobacterium violaceum
por: Teng, Li-Ping, et al.
Publicado: (2022)

Synthesis of ∆(3)-2-Hydroxybakuchiol Analogues and Their Growth Inhibitory Activity against Rat UMR106 Cells
por: Zhao, Qun, et al.
Publicado: (2014)

Sodium Dichloroacetate Stimulates Angiogenesis by Improving Endothelial Precursor Cell Function in an AKT/GSK-3β/Nrf2 Dependent Pathway in Vascular Dementia Rats
por: Zhao, Hui, et al.
Publicado: (2019)

Discovery of a New Xanthone against Glioma: Synthesis and Development of (Pro)liposome Formulations
por: Alves, Ana, et al.
Publicado: (2019)

Synthesis and spectroscopic properties of β-triazoloporphyrin–xanthone dyads
por: Singh, Dileep Kumar, et al.
Publicado: (2015)

Plant-Derived Xanthones against Clostridial Enteric Infections
por: Liu, Ying, et al.
Publicado: (2023)

UPLC-PDA-QTOFMS-guided isolation of prenylated xanthones and benzoylphloroglucinols from the leaves of Garcinia oblongifolia and their migration-inhibitory activity
por: Zhang, Hong, et al.
Publicado: (2016)

Antibacterial and EGFR-Tyrosine Kinase Inhibitory Activities of Polyhydroxylated Xanthones from Garcinia succifolia
por: Duangsrisai, Susawat, et al.
Publicado: (2014)

Anti-Inflammatory Dipeptide, a Metabolite from Ambioba Secretion, Protects Cerebral Ischemia Injury by Blocking Apoptosis Via p-JNK/Bax Pathway
por: Zhang, Qian, et al.
Publicado: (2021)

Corrigendum: UPLC-PDA-QTOFMS-guided isolation of prenylated xanthones and benzoylphloroglucinols from the leaves of Garcinia oblongifolia and their migration-inhibitory activity
por: Zhang, Hong, et al.
Publicado: (2016)

Xanthones Active against Multidrug Resistance and Virulence Mechanisms of Bacteria
por: Durães, Fernando, et al.
Publicado: (2021)

Hydroxy-xanthones as promising antiviral agents: Synthesis and biological evaluation against human coronavirus OC43
por: Dean, Bethanie, et al.
Publicado: (2023)

Xanthones from the Pericarp of Garcinia mangostana
por: Yang, Renyue, et al.
Publicado: (2017)

Coumarins, Xanthones and Related Compounds
por: Richomme, Pascal
Publicado: (2016)

Synthesis and Evaluation of Spumigin Analogues Library with Thrombin Inhibitory Activity
por: Žula, Aleš, et al.
Publicado: (2018)

Antioxidant, Antimicrobial and Tyrosinase Inhibitory Activities of Xanthones Isolated from Artocarpus obtusus F.M. Jarrett
por: Hashim, Najihah Mohd., et al.
Publicado: (2012)

Differential effects of staurosporine analogues on cell cycle, growth and viability in A549 cells.
por: Courage, C., et al.
Publicado: (1996)

Identification of Xanthones from the Mangosteen Pericarp that Inhibit the Growth of Ralstonia solanacearum
por: Li, Ping, et al.
Publicado: (2019)

Synthesis of a Small Library of Nature-Inspired Xanthones and Study of Their Antimicrobial Activity
por: Resende, Diana I. S. P., et al.
Publicado: (2020)

The Involvement of Xanthone and (E)-Cinnamoyl Chromophores for the Design and Synthesis of Novel Sunscreening Agents
por: Popiół, Justyna, et al.
Publicado: (2020)

Marine-Derived Xanthone from 2010 to 2021: Isolation, Bioactivities and Total Synthesis
por: Veríssimo, Ana C. S., et al.
Publicado: (2022)

Design, Synthesis, Biological Evaluation, and Preliminary Mechanistic Study of a Novel Mitochondrial-Targeted Xanthone
por: Wang, Sibei, et al.
Publicado: (2023)

Sulforaphane Analogues with Heterocyclic Moieties: Syntheses and Inhibitory Activities against Cancer Cell Lines
por: Shi, Ye-Hui, et al.
Publicado: (2016)

Antitumor Activity of Some Prenylated Xanthones
por: Castanheiro, Raquel A. P., et al.
Publicado: (2009)

Chiral Derivatives of Xanthones with Antimicrobial Activity
por: Araújo, Joana, et al.
Publicado: (2019)

Bioactive Marine Xanthones: A Review
por: Soares, José X., et al.
Publicado: (2022)

From Natural Xanthones to Synthetic C-1 Aminated 3,4-Dioxygenated Xanthones as Optimized Antifouling Agents
por: Resende, Diana I. S. P., et al.
Publicado: (2021)

Synthesis and Cell Growth Inhibitory Activity of Six Non‐glycosaminoglycan‐Type Heparin‐Analogue Trisaccharides
por: Lisztes, Erika, et al.
Publicado: (2021)

Heterocyclic Analogues of Xanthone and Xanthione. 1H-Pyrano[2,3-c:6,5-c]dipyrazol-4(7H)-ones and Thiones: Synthesis and NMR Data
por: Datterl, Barbara, et al.
Publicado: (2010)

verA Gene is Involved in the Step to Make the Xanthone Structure of Demethylsterigmatocystin in Aflatoxin Biosynthesis
por: Zeng, Hongmei, et al.
Publicado: (2020)

Retraction: Synthesis of xanthone derivatives and anti-hepatocellular carcinoma potency evaluation: induced apoptosis
por: Fisher, Laura
Publicado: (2022)

Chemical and Biological Research on Herbal Medicines Rich in Xanthones
por: Ruan, Jingya, et al.
Publicado: (2017)

Cladoxanthones C–G, xanthone derivatives from Cladosporium sp.
por: Zhang, Yiqing, et al.
Publicado: (2023)

Cytotoxic Xanthones from Hypericum stellatum, an Ethnomedicine in Southwest China
por: Ji, Yuanyuan, et al.
Publicado: (2019)

Effect of Xanthone Derivatives on Animal Models of Depression
por: Zhao, Xu, et al.
Publicado: (2014)

Lichen Xanthones as Models for New Antifungal Agents
por: Resende, Diana I. S. P., et al.
Publicado: (2018)

Xanthones of Lichen Source: A 2016 Update
por: Le Pogam, Pierre, et al.
Publicado: (2016)

Xanthones from the Roots of Moutabea guianensis Aubl.
por: Filho, Haroldo da S. Ripardo, et al.
Publicado: (2014)

Xanthone Biosynthetic Pathway in Plants: A Review
por: Remali, Juwairiah, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_rc5nqju9deeb3tdem68k5b1gm1