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A comparison of mechanistic signaling pathway activity analysis methods

Understanding the aspects of cell functionality that account for disease mechanisms or drug modes of action is a main challenge for precision medicine. Classical gene-based approaches ignore the modular nature of most human traits, whereas conventional pathway enrichment approaches produce only illu...

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Detalles Bibliográficos
Autores principales: Amadoz, Alicia, Hidalgo, Marta R, Çubuk, Cankut, Carbonell-Caballero, José, Dopazo, Joaquín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917216/
https://www.ncbi.nlm.nih.gov/pubmed/29868818
http://dx.doi.org/10.1093/bib/bby040

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