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Tyrphostin AG490 reduces inflammation and fibrosis in neonatal obstructive nephropathy

BACKGROUND: Congenital obstructive nephropathy is the main cause of end-stage renal disease in infants and children. Renal insufficiency is due to impaired growth and maturation in the developing kidney with obstruction. Congenital obstructive nephropathy leads to cytokine mediated inflammation and...

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Detalles Bibliográficos
Autores principales:	Gasparitsch, Mojca, Schieber, Alexandra, Schaubeck, Teresa, Keller, Ursula, Cattaruzza, Marco, Lange-Sperandio, Bärbel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917291/ https://www.ncbi.nlm.nih.gov/pubmed/31846485 http://dx.doi.org/10.1371/journal.pone.0226675

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