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Joint Location–Specific JAK‐STAT Signaling in Rheumatoid Arthritis Fibroblast‐like Synoviocytes

OBJECTIVE: Rheumatoid arthritis (RA) fibroblast‐like synoviocytes (FLS) derived from hip and knee have distinctive DNA methylation and transcriptome patterns in interleukin (IL)‐6 signaling and Janus kinase (JAK)–signal transducers and activators of transcription (STAT) pathways. To determine the fu...

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Detalles Bibliográficos
Autores principales: Hammaker, Deepa, Nygaard, Gyrid, Kuhs, Amanda, Ai, Rizi, Boyle, David L., Wang, Wei, Firestein, Gary S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917316/
https://www.ncbi.nlm.nih.gov/pubmed/31872186
http://dx.doi.org/10.1002/acr2.11093