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Joint Location–Specific JAK‐STAT Signaling in Rheumatoid Arthritis Fibroblast‐like Synoviocytes
OBJECTIVE: Rheumatoid arthritis (RA) fibroblast‐like synoviocytes (FLS) derived from hip and knee have distinctive DNA methylation and transcriptome patterns in interleukin (IL)‐6 signaling and Janus kinase (JAK)–signal transducers and activators of transcription (STAT) pathways. To determine the fu...
Autores principales: | Hammaker, Deepa, Nygaard, Gyrid, Kuhs, Amanda, Ai, Rizi, Boyle, David L., Wang, Wei, Firestein, Gary S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917316/ https://www.ncbi.nlm.nih.gov/pubmed/31872186 http://dx.doi.org/10.1002/acr2.11093 |
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