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Gene Expression Meta‐Analysis Reveals Concordance in Gene Activation, Pathway, and Cell‐Type Enrichment in Dermatomyositis Target Tissues

OBJECTIVE: We conducted a comprehensive gene expression meta‐analysis in dermatomyositis (DM) muscle and skin tissues to identify shared disease‐relevant genes and pathways across tissues. METHODS: Six publicly available data sets from DM muscle and two from skin were identified. Meta‐analysis was p...

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Detalles Bibliográficos
Autores principales: Neely, Jessica, Rychkov, Dmitry, Paranjpe, Manish, Waterfield, Michael, Kim, Susan, Sirota, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917332/
https://www.ncbi.nlm.nih.gov/pubmed/31872188
http://dx.doi.org/10.1002/acr2.11081