The interferon-gamma pathway is selectively up-regulated in the liver of patients with secondary hemophagocytic lymphohistiocytosis

Aim of this study was to investigate the activation of the IFNγ pathway in the affected liver and in the blood of patients with secondary hemophagocytic lymphohistiocytosis (sHLH). To this purpose, the mRNA expression levels of IFNG and IFNγ-inducible genes as well as Tyrosine (701)-phosphorylated s...

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Detalles Bibliográficos
Autores principales: Prencipe, Giusi, Bracaglia, Claudia, Caiello, Ivan, Pascarella, Antonia, Francalanci, Paola, Pardeo, Manuela, Meneghel, Alessandra, Martini, Giorgia, Rossi, Marianna N., Insalaco, Antonella, Marucci, Giulia, Nobili, Valerio, Spada, Marco, Zulian, Francesco, De Benedetti, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917341/
https://www.ncbi.nlm.nih.gov/pubmed/31846457
http://dx.doi.org/10.1371/journal.pone.0226043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917341/
https://www.ncbi.nlm.nih.gov/pubmed/31846457
http://dx.doi.org/10.1371/journal.pone.0226043

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