Har-P, a short P-element variant, weaponizes P-transposase to severely impair Drosophila development

Without transposon-silencing Piwi-interacting RNAs (piRNAs), transposition causes an ovarian atrophy syndrome in Drosophila called gonadal dysgenesis (GD). Harwich (Har) strains with P-elements cause severe GD in F1 daughters when Har fathers mate with mothers lacking P-element-piRNAs (i.e. ISO1 str...

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Detalles Bibliográficos
Autores principales: Srivastav, Satyam P, Rahman, Reazur, Ma, Qicheng, Pierre, Jasmine, Bandyopadhyay, Saptaparni, Lau, Nelson C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917496/
https://www.ncbi.nlm.nih.gov/pubmed/31845649
http://dx.doi.org/10.7554/eLife.49948

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