Clinical significance of TP53 variants as possible secondary findings in tumor-only next-generation sequencing

In tumor-only next-generation sequencing (NGS), identified variants have the potential to be secondary findings (SFs), but they require verification through additional germline testing. In the present study, 194 patients with advanced cancer who underwent tumor-only NGS between April 2015 and March...

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Detalles Bibliográficos
Autores principales: Yamamoto, Yoshihiro, Kanai, Masashi, Kou, Tadayuki, Sugiyama, Aiko, Nakamura, Eijiro, Miyake, Hidehiko, Yamada, Takahiro, Nishigaki, Masakazu, Kondo, Tomohiro, Murakami, Hiromi, Torishima, Masako, Matsumoto, Shigemi, Kosugi, Shinji, Muto, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917569/
https://www.ncbi.nlm.nih.gov/pubmed/31628423
http://dx.doi.org/10.1038/s10038-019-0681-6

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