Digital image analysis of multiplex fluorescence IHC in colorectal cancer recognizes the prognostic value of CDX2 and its negative correlation with SOX2

Flourescence-based multiplex immunohistochemistry (mIHC) combined with multispectral imaging and digital image analysis (DIA) is a quantitative high-resolution method for determination of protein expression in tissue. We applied this method for five biomarkers (CDX2, SOX2, SOX9, E-cadherin, and β-ca...

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Detalles Bibliográficos
Autores principales: Lopes, Nair, Bergsland, Christian Holst, Bjørnslett, Merete, Pellinen, Teijo, Svindland, Aud, Nesbakken, Arild, Almeida, Raquel, Lothe, Ragnhild A., David, Leonor, Bruun, Jarle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2019
Materias:
Technical Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917572/
https://www.ncbi.nlm.nih.gov/pubmed/31641225
http://dx.doi.org/10.1038/s41374-019-0336-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917572/
https://www.ncbi.nlm.nih.gov/pubmed/31641225
http://dx.doi.org/10.1038/s41374-019-0336-4

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